CRYOSEEKTHE MOLECULAR COLLECTION

FIBRIL FORMS / 01

THE MOLECULAR COLLECTION / 2025
Fibril structures · CryoSeekVOL. 01

FIBRIL
FORMS

GF-3BH2 Structure on a transparent background
50STRUCTURES
10 SUBCLASSES
CRYOSEEK / FIG. 0200
READING THE FORMS / NOMENCLATURE

Small scale.
Endless form.

Original blue glycans and purple protein core
A LANGUAGE OF STRUCTURE

GF–3BH2

GF
Glycofibril
3BH
Trimeric β-helical core
2
Index within the subclass

Blue glycans surround
a purple protein core.

50 STRUCTURES / 10 SUBCLASSES
CRYOSEEK / FIG. 0201
THE COLLECTION / CONTENTS

One world.
Fifty forms.

13 PROTEIN FIBRILS / 37 GLYCOFIBRILSCOUNT / PAGE
01
PF-PLLPilus-like fibrils
1303
02
GF-IPTIPT domains
0117
03
GF-1BHSingle-chain β-helix
0218
04
GF-3BHTrimeric β-helix
0321
05
GF-1L2RDipeptide repeats
0825
06
GF-1L4RTetrapeptide repeats
0834
07
GF-1L6RHexapeptide repeats
0143
08
GF-1L8ROctapeptide repeats
0144
09
GF-3L3RTripeptide repeats
0245
10
GF-NPGlycan-only fibrils
1148

Subclasses with multiple structures open with an overview.
Use the subclass menu to navigate.

CRYOSEEK / FIG. 0202
SUBCLASS 01 / PILUS-LIKE

PF-PLL

Pilus-like fibrils

13FORMS
PF-PLL1，2.87 Å
PF-PLL12.87 Å
PF-PLL2，2.85 Å
PF-PLL22.85 Å
PF-PLL3，2.59 Å
PF-PLL32.59 Å
PF-PLL4，2.26 Å
PF-PLL42.26 Å
PF-PLL5，3.37 Å
PF-PLL53.37 Å
PF-PLL6，2.70 Å
PF-PLL62.70 Å
PF-PLL7，3.66 Å
PF-PLL73.66 Å
PF-PLL8，2.73 Å
PF-PLL82.73 Å
PF-PLL9，2.35 Å
PF-PLL92.35 Å
PF-PLL10，2.36 Å
PF-PLL102.36 Å
PF-PLL11，3.44 Å
PF-PLL113.44 Å
PF-PLL12，3.56 Å
PF-PLL123.56 Å
PF-PLL13，3.73 Å
PF-PLL133.73 Å
Protein fibrils with pilus-like assembly.Overview → Individual structures
CRYOSEEK / FIG. 0203
SUBCLASS 01 / PILUS-LIKE01 OF 13
01
Pilus-like fibrils

PF—PLL1

PF-PLL1 Complete cryo-EM structure
RESOLUTION2.87Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL1CRYO-EM DENSITY
CRYOSEEK / FIG. 0204
SUBCLASS 01 / PILUS-LIKE02 OF 13
02
Pilus-like fibrils

PF—PLL2

PF-PLL2 Complete cryo-EM structure
RESOLUTION2.85Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL2CRYO-EM DENSITY
CRYOSEEK / FIG. 0205
SUBCLASS 01 / PILUS-LIKE03 OF 13
03
Pilus-like fibrils

PF—PLL3

PF-PLL3 Complete cryo-EM structure
RESOLUTION2.59Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL3CRYO-EM DENSITY
CRYOSEEK / FIG. 0206
SUBCLASS 01 / PILUS-LIKE04 OF 13
04
Pilus-like fibrils

PF—PLL4

PF-PLL4 Complete cryo-EM structure
RESOLUTION2.26Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL4CRYO-EM DENSITY
CRYOSEEK / FIG. 0207
SUBCLASS 01 / PILUS-LIKE05 OF 13
05
Pilus-like fibrils

PF—PLL5

PF-PLL5 Complete cryo-EM structure
RESOLUTION3.37Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL5CRYO-EM DENSITY
CRYOSEEK / FIG. 0208
SUBCLASS 01 / PILUS-LIKE06 OF 13
06
Pilus-like fibrils

PF—PLL6

PF-PLL6 Complete cryo-EM structure
RESOLUTION2.70Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL6CRYO-EM DENSITY
CRYOSEEK / FIG. 0209
SUBCLASS 01 / PILUS-LIKE07 OF 13
07
Pilus-like fibrils

PF—PLL7

PF-PLL7 Complete cryo-EM structure
RESOLUTION3.66Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL7CRYO-EM DENSITY
CRYOSEEK / FIG. 0210
SUBCLASS 01 / PILUS-LIKE08 OF 13
08
Pilus-like fibrils

PF—PLL8

PF-PLL8 Complete cryo-EM structure
RESOLUTION2.73Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL8CRYO-EM DENSITY
CRYOSEEK / FIG. 0211
SUBCLASS 01 / PILUS-LIKE09 OF 13
09
Pilus-like fibrils

PF—PLL9

PF-PLL9 Complete cryo-EM structure
RESOLUTION2.35Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL9CRYO-EM DENSITY
CRYOSEEK / FIG. 0212
SUBCLASS 01 / PILUS-LIKE10 OF 13
10
Pilus-like fibrils

PF—PLL10

PF-PLL10 Complete cryo-EM structure
RESOLUTION2.36Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL10CRYO-EM DENSITY
CRYOSEEK / FIG. 0213
SUBCLASS 01 / PILUS-LIKE11 OF 13
11
Pilus-like fibrils

PF—PLL11

PF-PLL11 Complete cryo-EM structure
RESOLUTION3.44Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL11CRYO-EM DENSITY
CRYOSEEK / FIG. 0214
SUBCLASS 01 / PILUS-LIKE12 OF 13
12
Pilus-like fibrils

PF—PLL12

PF-PLL12 Complete cryo-EM structure
RESOLUTION3.56Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL12CRYO-EM DENSITY
CRYOSEEK / FIG. 0215
SUBCLASS 01 / PILUS-LIKE13 OF 13
13
Pilus-like fibrils

PF—PLL13

PF-PLL13 Complete cryo-EM structure
RESOLUTION3.73Å

Protein fibrils with pilus-like assembly.
Pilus-like protein fibrils

PF-PLL13CRYO-EM DENSITY
CRYOSEEK / FIG. 0216
SUBCLASS 02 / IPT DOMAIN01 OF 01
01
IPT domains

GF—IPT1

GF-IPT1 Complete cryo-EM structure
RESOLUTION2.53Å

A protein core composed of consecutive IPT domains.
IPT-domain glycofibrils

GF-IPT1CRYO-EM DENSITY
CRYOSEEK / FIG. 0217
SUBCLASS 03 / SINGLE HELIX

GF-1BH

Single-chain β-helix

02FORMS
GF-1BH1，2.54 Å
GF-1BH12.54 Å
GF-1BH2，3.11 Å
GF-1BH23.11 Å
One protein chain forms the β-helical core.Overview → Individual structures
CRYOSEEK / FIG. 0218
SUBCLASS 03 / SINGLE HELIX01 OF 02
01
Single-chain β-helix

GF—1BH1

GF-1BH1 Complete cryo-EM structure
RESOLUTION2.54Å

One protein chain forms the β-helical core.
Single-chain beta helix

GF-1BH1CRYO-EM DENSITY
CRYOSEEK / FIG. 0219
SUBCLASS 03 / SINGLE HELIX02 OF 02
02
Single-chain β-helix

GF—1BH2

GF-1BH2 Complete cryo-EM structure
RESOLUTION3.11Å

One protein chain forms the β-helical core.
Single-chain beta helix

GF-1BH2CRYO-EM DENSITY
CRYOSEEK / FIG. 0220
SUBCLASS 04 / TRIPLE HELIX

GF-3BH

Trimeric β-helix

03FORMS
GF-3BH1，2.35 Å
GF-3BH12.35 Å
GF-3BH2，2.63 Å
GF-3BH22.63 Å
GF-3BH3，2.66 Å
GF-3BH32.66 Å
Three protein chains form a β-helical core.Overview → Individual structures
CRYOSEEK / FIG. 0221
SUBCLASS 04 / TRIPLE HELIX01 OF 03
01
Trimeric β-helix

GF—3BH1

GF-3BH1 Complete cryo-EM structure
RESOLUTION2.35Å

Three protein chains form a β-helical core.
Three-chain beta helix

GF-3BH1CRYO-EM DENSITY
CRYOSEEK / FIG. 0222
SUBCLASS 04 / TRIPLE HELIX02 OF 03
02
Trimeric β-helix

GF—3BH2

GF-3BH2 Complete cryo-EM structure
RESOLUTION2.63Å

Three protein chains form a β-helical core.
Three-chain beta helix

GF-3BH2CRYO-EM DENSITY
CRYOSEEK / FIG. 0223
SUBCLASS 04 / TRIPLE HELIX03 OF 03
03
Trimeric β-helix

GF—3BH3

GF-3BH3 Complete cryo-EM structure
RESOLUTION2.66Å

Three protein chains form a β-helical core.
Three-chain beta helix

GF-3BH3CRYO-EM DENSITY
CRYOSEEK / FIG. 0224
SUBCLASS 05 / TWO RESIDUES

GF-1L2R

Dipeptide repeats

08FORMS
GF-1L2R1，2.80 Å
GF-1L2R12.80 Å
GF-1L2R2，2.58 Å
GF-1L2R22.58 Å
GF-1L2R3，2.90 Å
GF-1L2R32.90 Å
GF-1L2R4，2.67 Å
GF-1L2R42.67 Å
GF-1L2R5，2.53 Å
GF-1L2R52.53 Å
GF-1L2R6，2.83 Å
GF-1L2R62.83 Å
GF-1L2R7，2.74 Å
GF-1L2R72.74 Å
GF-1L2R8，2.88 Å
GF-1L2R82.88 Å
A single linear chain with two-residue repeats.Overview → Individual structures
CRYOSEEK / FIG. 0225
SUBCLASS 05 / TWO RESIDUES01 OF 08
01
Dipeptide repeats

GF—1L2R1

GF-1L2R1 Complete cryo-EM structure
RESOLUTION2.80Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R1CRYO-EM DENSITY
CRYOSEEK / FIG. 0226
SUBCLASS 05 / TWO RESIDUES02 OF 08
02
Dipeptide repeats

GF—1L2R2

GF-1L2R2 Complete cryo-EM structure
RESOLUTION2.58Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R2CRYO-EM DENSITY
CRYOSEEK / FIG. 0227
SUBCLASS 05 / TWO RESIDUES03 OF 08
03
Dipeptide repeats

GF—1L2R3

GF-1L2R3 Complete cryo-EM structure
RESOLUTION2.90Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R3CRYO-EM DENSITY
CRYOSEEK / FIG. 0228
SUBCLASS 05 / TWO RESIDUES04 OF 08
04
Dipeptide repeats

GF—1L2R4

GF-1L2R4 Complete cryo-EM structure
RESOLUTION2.67Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R4CRYO-EM DENSITY
CRYOSEEK / FIG. 0229
SUBCLASS 05 / TWO RESIDUES05 OF 08
05
Dipeptide repeats

GF—1L2R5

GF-1L2R5 Complete cryo-EM structure
RESOLUTION2.53Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R5CRYO-EM DENSITY
CRYOSEEK / FIG. 0230
SUBCLASS 05 / TWO RESIDUES06 OF 08
06
Dipeptide repeats

GF—1L2R6

GF-1L2R6 Complete cryo-EM structure
RESOLUTION2.83Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R6CRYO-EM DENSITY
CRYOSEEK / FIG. 0231
SUBCLASS 05 / TWO RESIDUES07 OF 08
07
Dipeptide repeats

GF—1L2R7

GF-1L2R7 Complete cryo-EM structure
RESOLUTION2.74Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R7CRYO-EM DENSITY
CRYOSEEK / FIG. 0232
SUBCLASS 05 / TWO RESIDUES08 OF 08
08
Dipeptide repeats

GF—1L2R8

GF-1L2R8 Complete cryo-EM structure
RESOLUTION2.88Å

A single linear chain with two-residue repeats.
Two-residue repeats

GF-1L2R8CRYO-EM DENSITY
CRYOSEEK / FIG. 0233
SUBCLASS 06 / FOUR RESIDUES

GF-1L4R

Tetrapeptide repeats

08FORMS
GF-1L4R1，3.06 Å
GF-1L4R13.06 Å
GF-1L4R2，2.60 Å
GF-1L4R22.60 Å
GF-1L4R3，2.92 Å
GF-1L4R32.92 Å
GF-1L4R4，3.42 Å
GF-1L4R43.42 Å
GF-1L4R5，3.56 Å
GF-1L4R53.56 Å
GF-1L4R6，3.55 Å
GF-1L4R63.55 Å
GF-1L4R7，2.81 Å
GF-1L4R72.81 Å
GF-1L4R8，2.78 Å
GF-1L4R82.78 Å
A single linear chain with four-residue repeats.Overview → Individual structures
CRYOSEEK / FIG. 0234
SUBCLASS 06 / FOUR RESIDUES01 OF 08
01
Tetrapeptide repeats

GF—1L4R1

GF-1L4R1 Complete cryo-EM structure
RESOLUTION3.06Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R1CRYO-EM DENSITY
CRYOSEEK / FIG. 0235
SUBCLASS 06 / FOUR RESIDUES02 OF 08
02
Tetrapeptide repeats

GF—1L4R2

GF-1L4R2 Complete cryo-EM structure
RESOLUTION2.60Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R2CRYO-EM DENSITY
CRYOSEEK / FIG. 0236
SUBCLASS 06 / FOUR RESIDUES03 OF 08
03
Tetrapeptide repeats

GF—1L4R3

GF-1L4R3 Complete cryo-EM structure
RESOLUTION2.92Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R3CRYO-EM DENSITY
CRYOSEEK / FIG. 0237
SUBCLASS 06 / FOUR RESIDUES04 OF 08
04
Tetrapeptide repeats

GF—1L4R4

GF-1L4R4 Complete cryo-EM structure
RESOLUTION3.42Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R4CRYO-EM DENSITY
CRYOSEEK / FIG. 0238
SUBCLASS 06 / FOUR RESIDUES05 OF 08
05
Tetrapeptide repeats

GF—1L4R5

GF-1L4R5 Complete cryo-EM structure
RESOLUTION3.56Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R5CRYO-EM DENSITY
CRYOSEEK / FIG. 0239
SUBCLASS 06 / FOUR RESIDUES06 OF 08
06
Tetrapeptide repeats

GF—1L4R6

GF-1L4R6 Complete cryo-EM structure
RESOLUTION3.55Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R6CRYO-EM DENSITY
CRYOSEEK / FIG. 0240
SUBCLASS 06 / FOUR RESIDUES07 OF 08
07
Tetrapeptide repeats

GF—1L4R7

GF-1L4R7 Complete cryo-EM structure
RESOLUTION2.81Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R7CRYO-EM DENSITY
CRYOSEEK / FIG. 0241
SUBCLASS 06 / FOUR RESIDUES08 OF 08
08
Tetrapeptide repeats

GF—1L4R8

GF-1L4R8 Complete cryo-EM structure
RESOLUTION2.78Å

A single linear chain with four-residue repeats.
Four-residue repeats

GF-1L4R8CRYO-EM DENSITY
CRYOSEEK / FIG. 0242
SUBCLASS 07 / SIX RESIDUES01 OF 01
01
Hexapeptide repeats

GF—1L6R1

GF-1L6R1 Complete cryo-EM structure
RESOLUTION3.56Å

A single linear chain with six-residue repeats.
Six-residue repeats

GF-1L6R1CRYO-EM DENSITY
CRYOSEEK / FIG. 0243
SUBCLASS 08 / EIGHT RESIDUES01 OF 01
01
Octapeptide repeats

GF—1L8R1

GF-1L8R1 Complete cryo-EM structure
RESOLUTION3.04Å

A single linear chain with eight-residue repeats.
Eight-residue repeats

GF-1L8R1CRYO-EM DENSITY
CRYOSEEK / FIG. 0244
SUBCLASS 09 / THREE BY THREE

GF-3L3R

Tripeptide repeats

02FORMS
GF-3L3R1，2.95 Å
GF-3L3R12.95 Å
GF-3L3R2，3.14 Å
GF-3L3R23.14 Å
Three linear chains with three-residue repeats.Overview → Individual structures
CRYOSEEK / FIG. 0245
SUBCLASS 09 / THREE BY THREE01 OF 02
01
Tripeptide repeats

GF—3L3R1

GF-3L3R1 Complete cryo-EM structure
RESOLUTION2.95Å

Three linear chains with three-residue repeats.
Three chains · three-residue repeats

GF-3L3R1CRYO-EM DENSITY
CRYOSEEK / FIG. 0246
SUBCLASS 09 / THREE BY THREE02 OF 02
02
Tripeptide repeats

GF—3L3R2

GF-3L3R2 Complete cryo-EM structure
RESOLUTION3.14Å

Three linear chains with three-residue repeats.
Three chains · three-residue repeats

GF-3L3R2CRYO-EM DENSITY
CRYOSEEK / FIG. 0247
SUBCLASS 10 / GLYCAN ONLY

GF-NP

Glycan-only fibrils

11FORMS
GF-NP1，3.84 Å
GF-NP13.84 Å
GF-NP2，2.83 Å
GF-NP22.83 Å
GF-NP3，2.97 Å
GF-NP32.97 Å
GF-NP4，2.98 Å
GF-NP42.98 Å
GF-NP5，2.22 Å
GF-NP52.22 Å
GF-NP6，3.33 Å
GF-NP63.33 Å
GF-NP7，3.23 Å
GF-NP73.23 Å
GF-NP8，2.33 Å
GF-NP82.33 Å
GF-NP9，2.40 Å
GF-NP92.40 Å
GF-NP10，3.00 Å
GF-NP103.00 Å
GF-NP11，2.66 Å
GF-NP112.66 Å
Fibrils composed entirely of glycans.Overview → Individual structures
CRYOSEEK / FIG. 0248
SUBCLASS 10 / GLYCAN ONLY01 OF 11
01
Glycan-only fibrils

GF—NP1

GF-NP1 Complete cryo-EM structure
RESOLUTION3.84Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP1CRYO-EM DENSITY
CRYOSEEK / FIG. 0249
SUBCLASS 10 / GLYCAN ONLY02 OF 11
02
Glycan-only fibrils

GF—NP2

GF-NP2 Complete cryo-EM structure
RESOLUTION2.83Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP2CRYO-EM DENSITY
CRYOSEEK / FIG. 0250
SUBCLASS 10 / GLYCAN ONLY03 OF 11
03
Glycan-only fibrils

GF—NP3

GF-NP3 Complete cryo-EM structure
RESOLUTION2.97Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP3CRYO-EM DENSITY
CRYOSEEK / FIG. 0251
SUBCLASS 10 / GLYCAN ONLY04 OF 11
04
Glycan-only fibrils

GF—NP4

GF-NP4 Complete cryo-EM structure
RESOLUTION2.98Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP4CRYO-EM DENSITY
CRYOSEEK / FIG. 0252
SUBCLASS 10 / GLYCAN ONLY05 OF 11
05
Glycan-only fibrils

GF—NP5

GF-NP5 Complete cryo-EM structure
RESOLUTION2.22Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP5CRYO-EM DENSITY
CRYOSEEK / FIG. 0253
SUBCLASS 10 / GLYCAN ONLY06 OF 11
06
Glycan-only fibrils

GF—NP6

GF-NP6 Complete cryo-EM structure
RESOLUTION3.33Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP6CRYO-EM DENSITY
CRYOSEEK / FIG. 0254
SUBCLASS 10 / GLYCAN ONLY07 OF 11
07
Glycan-only fibrils

GF—NP7

GF-NP7 Complete cryo-EM structure
RESOLUTION3.23Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP7CRYO-EM DENSITY
CRYOSEEK / FIG. 0255
SUBCLASS 10 / GLYCAN ONLY08 OF 11
08
Glycan-only fibrils

GF—NP8

GF-NP8 Complete cryo-EM structure
RESOLUTION2.33Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP8CRYO-EM DENSITY
CRYOSEEK / FIG. 0256
SUBCLASS 10 / GLYCAN ONLY09 OF 11
09
Glycan-only fibrils

GF—NP9

GF-NP9 Complete cryo-EM structure
RESOLUTION2.40Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP9CRYO-EM DENSITY
CRYOSEEK / FIG. 0257
SUBCLASS 10 / GLYCAN ONLY10 OF 11
10
Glycan-only fibrils

GF—NP10

GF-NP10 Complete cryo-EM structure
RESOLUTION3.00Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP10CRYO-EM DENSITY
CRYOSEEK / FIG. 0258
SUBCLASS 10 / GLYCAN ONLY11 OF 11
11
Glycan-only fibrils

GF—NP11

GF-NP11 Complete cryo-EM structure
RESOLUTION2.66Å

Fibrils composed entirely of glycans.
Glycan-only fibrils

GF-NP11CRYO-EM DENSITY
CRYOSEEK / FIG. 0259
SOURCE PUBLICATION

CryoSeek.

High-throughput cryo-EM characterization and automated model building of glycofibrils via CryoSeek

Hu et al. · 2025
LangTaoSha Preprint Server
20 November 2025

doi: 10.65215/bkvrt910

Institutional emblem
CRYOSEEK / FIG. 0260
CRYOSEEK / STRUCTURAL ATLAS
GF-NP1150 STRUCTURES / 10 SUBCLASSES
CRYOSEEK / FIG. 0261
PLATE VIEW

Cryo-EM reconstructions